Meet Your Doctor
Luke Sorrell, MD FACP
Board-certified internal medicine physician, Fellow of the American College of Physicians, A4M Fellowship in Longevity Medicine graduate, and founder of Sorrell MD — a precision longevity telemedicine practice serving patients in most U.S. states from Southlake, Texas.
At a glance
- Medical degree: The University of Texas Health Science Center at Houston (UTHealth Houston), 2017
- Residency: Internal Medicine, Baylor University Medical Center at Dallas, 2017–2020
- Board certification: American Board of Internal Medicine, certified 2020
- Fellow of the American College of Physicians (FACP): elected 2024
- Fellowship in Longevity Medicine: American Academy of Anti-Aging Medicine (A4M), completed June 2026
- Peptide therapy: Peptavo Certified Clinician, 2026
- Focus: longevity medicine, hormone and metabolic optimization, body composition, cardiovascular risk, gut health, fertility
- Licensure: Texas (primary) and most U.S. states — contact the practice for the current list
- Practice model: 100% telemedicine in most U.S. states — direct physician access, never a physician assistant
Advanced Training · Completed June 2026
Fellowship in Longevity Medicine
In June 2026 Dr. Sorrell completed the Fellowship in Longevity Medicine offered by the American Academy of Anti-Aging Medicine (A4M), the largest postgraduate training body in preventive, metabolic and longevity medicine. The fellowship is a physician-level curriculum that sits on top of his internal medicine board certification, adding formal training in the science of how people age and the clinical tools that measurably slow it.
- Endocrine and cardiometabolic optimization — hormones, heart health and metabolic resilience
- Neurovascular and metabolic synergy — the gut–brain connection for longevity
- Brain-first longevity — environmental triggers, neuroprotection and detoxification
- Gastro-nutritional strategies — precision gut health and diet optimization
- Clinical protocols — a systems-biology approach to longevity medicine
What this means for patients: the Sorrell MD Longevity Program is built by a physician trained in both conventional internal medicine and the longevity specialty — able to order and interpret any test, prescribe any medication, and place the newer tools of the field (biological-age testing, peptides, hormone optimization, advanced lipid and metabolic markers) in proper clinical context.
Background
Dr. Luke Sorrell earned his medical degree from the University of Texas Health Science Center at Houston and completed his internal medicine internship and residency at Baylor University Medical Center at Dallas. He was board certified by the American Board of Internal Medicine in 2020 and elected a Fellow of the American College of Physicians in 2024.
His first year out of residency was spent as a hospitalist at Baylor University Medical Center at Dallas, working with the hospital medicine and procedure teams — which is to say, meeting patients at the point where preventable disease had already become unpreventable. He then spent several years in primary care in McKinney and Plano, where the same pattern repeated at a slower tempo: conditions that had been building silently for fifteen or twenty years, and roughly seven minutes in which to address them.
In late 2024 he moved into concierge longevity medicine at Gladden Longevity in the Dallas area, working with high-functioning executives on preventive and longevity care. He founded Sorrell MD in March 2026 to practice that medicine on his own terms: deep diagnostics, personalized protocols, and enough time to actually use them. In 2026 he completed the A4M Fellowship in Longevity Medicine and the Peptavo Peptide Therapy Certification, formalizing the training behind the practice.
Dr. Sorrell also served as an adjunct lecturer at Texas A&M University College of Medicine's Dallas campus from 2018 to 2021, precepting medical students in history-taking, physical examination and oral presentation.
Clinical Approach
A standard annual physical measures somewhere between fifteen and thirty biomarkers. A Sorrell MD workup measures 100 to 200 or more, selected against the patient's symptoms and goals: a full hormonal profile, advanced metabolic markers such as fasting insulin and HOMA-IR, cardiovascular markers including ApoB, Lp(a) and hs-CRP, nutrient status, and functional testing where it is warranted.
The point of that depth is not the data. It is that root causes are usually invisible at standard resolution — and once they are visible, they are frequently treatable years before they would otherwise surface as disease. Read more about root cause medicine and what a longevity doctor actually does.
Education & Training
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June 2026Fellowship in Longevity Medicine
American Academy of Anti-Aging Medicine (A4M)
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2017 – 2020Internal Medicine Residency & Internship
Baylor University Medical Center at Dallas — Dallas, TX
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2013 – 2017Doctor of Medicine (MD)
The University of Texas Health Science Center at Houston (UTHealth Houston) — Houston, TX
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2009 – 2013Bachelor of Science, Biochemistry
Abilene Christian University — Abilene, TX. Honors College graduate.
Certifications & Licensure
- Certified 2020 American Board of Internal Medicine Board certified in internal medicine. Verify credential →
- Elected 2024 Fellow, American College of Physicians (FACP) Elected fellowship recognizing demonstrated excellence and professional accomplishment in internal medicine.
- Completed June 2026 Fellowship in Longevity Medicine — American Academy of Anti-Aging Medicine (A4M) Postgraduate physician fellowship in endocrine and cardiometabolic optimization, the gut–brain–metabolic axis, neuroprotection, precision nutrition and systems-biology longevity protocols. About the fellowship →
- Certified September 2026 Peptavo Certified Clinician — Peptide Therapy Certification Evidence-informed peptide medicine. Credential ID PEP-YP56R-Y0EKG. Verify credential →
- Licensure Licensed in Texas and most U.S. states Primary licensure with the Texas Medical Board, with active medical licenses in most U.S. states. Contact the practice for the current list of states.
Professional Affiliations
- American College of Physicians (Fellow)
- American Academy of Anti-Aging Medicine (A4M)
- American Medical Association
- Texas Medical Association
- Dallas County Medical Society
- Longevity Docs
Research & Presentations
Dr. Sorrell's research background spans thoracic and cardiovascular surgery outcomes at MD Anderson Cancer Center, gastroenterology at the Ertan Digestive Disease Center, ophthalmology at the Ruiz Department of Ophthalmology and Visual Science, and enzyme biochemistry at Abilene Christian University. His case reports and research have been presented at the American Thoracic Society International Conference, the American College of Physicians North Texas Regional Conference, and Baylor University Medical Center Grand Rounds.
Advisory work
Alongside clinical practice, Dr. Sorrell serves as a medical advisor to several health technology companies, including Tulu Health, Empower Health and CognomIQ — work focused on bringing precision and longevity medicine into scalable clinical systems.
Areas of Practice
- Comprehensive Longevity Program — concierge longevity care with included diagnostics
- Hormone, Body Composition & Metabolic Therapy — HRT, TRT, GLP-1 therapy with muscle preservation, peptides
- Hormone Replacement Therapy — for men and women
- Body Composition Optimization — the drivers of fat gain and muscle loss
- Cardiovascular Risk Assessment — advanced lipids, inflammatory markers, imaging
- Gut Optimization — microbiome and functional testing
- Fertility Optimization — for men and women
- Root Cause Analysis — chronic fatigue, brain fog, metabolic dysfunction
- Chat-Based Care — message Dr. Sorrell directly
Writing
Dr. Sorrell writes regularly on hormones, metabolic health, longevity research and cardiovascular risk. Recent pieces include the one cardiovascular test almost nobody is given, why fasting glucose and A1c miss early insulin resistance, the two measurements that predict lifespan better than most lab values, and why he practices precision longevity medicine. The full archive is on the Sorrell MD blog, and new articles go out first on Substack.
Podcast Appearances
Dr. Sorrell has been a two-time guest on the Fit Over 50 Life podcast with hosts Mark Patrick and Kelli Calabrese, talking through the testing that shows how fast a person is actually aging.
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Chronological Age vs. Biological Age: The Test That Exposes the Truth
Dr. Sorrell reviews host Mark Patrick’s TruAge epigenetic test live on air: what DNA methylation measures, how an overall biological age differs from organ-system ages and pace of aging, what telomere and inflammation results mean, and which habits, starting with sleep, move the numbers.
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The Longevity Tests That Could Save Your Life
Why a standard annual physical misses early disease, and the testing that finds it: lipid markers beyond LDL including Lp(a), how genetics shape statin response, brain-health testing and Alzheimer’s risk, DEXA for bone density and body composition, and biological-age testing.
Both episodes were recorded while Dr. Sorrell practiced at Gladden Longevity, before he founded Sorrell MD, so references to that practice reflect his role at the time.
Frequently Asked Questions
Is Dr. Luke Sorrell board certified?
Yes. Dr. Sorrell has been board certified in internal medicine by the American Board of Internal Medicine since 2020, and his certification can be verified online. He was elected a Fellow of the American College of Physicians (FACP) in 2024.
What is the A4M Fellowship in Longevity Medicine?
The Fellowship in Longevity Medicine is a postgraduate physician training program from the American Academy of Anti-Aging Medicine (A4M). Its core modules cover endocrine and cardiometabolic optimization, the gut–brain–metabolic connection, neuroprotection and environmental medicine, precision nutrition and microbiome science, and systems-biology clinical protocols. Dr. Sorrell completed the fellowship in June 2026.
What kind of doctor is Dr. Sorrell?
Dr. Sorrell is a board-certified internal medicine physician who practices longevity and precision medicine. He trained as an internist at Baylor University Medical Center at Dallas, worked as a hospitalist and then in primary care, and moved into concierge longevity medicine before founding Sorrell MD. His practice focuses on hormone and metabolic optimization, body composition, cardiovascular risk, gut health and fertility.
Can I see Dr. Sorrell if I do not live in Texas?
Very likely. Sorrell MD is a telemedicine practice and Dr. Sorrell is licensed in Texas and most other U.S. states; contact the practice to confirm coverage in yours. Labs are drawn at a Quest, LabCorp or hospital laboratory near you, imaging is scheduled locally, and all visits and messaging happen online. In-person appointments in Southlake, Texas are available by request.
Will I see Dr. Sorrell directly, or a physician assistant?
Every patient works directly with Dr. Sorrell. Sorrell MD does not use physician assistants or nurse practitioners; every appointment, message and protocol decision is handled by the physician.
Is Sorrell MD a single-physician practice, and what does that mean for continuity?
Yes, by design. Every patient sees the same board-certified internist at every visit and every message is answered by him, which is the reason the practice exists. Continuity is protected in practical ways: patients own their records and can export them at any time, labs run through national laboratories and stay accessible in the patient's own accounts, prescriptions are filled at the patient's own pharmacy, and monthly memberships carry no long-term contract. Planned absences are communicated in advance with guidance for time-sensitive needs. Sorrell MD is not an emergency service; urgent symptoms are always directed to local emergency care.
How does Sorrell MD decide what to test and what to prescribe?
Every recommendation is sorted into one of three evidence tiers and labelled as such: guideline-based prevention first, strong-but-emerging options once those are in place, and experimental or off-label therapies only case by case with written consent. Testing is baseline for everyone, risk-directed after that, and repeated on a schedule tied to what is being treated. The full policy, including what the practice will not prescribe, is published at How We Decide.
Practice Details
Sorrell MD operates entirely by telemedicine. It is a direct-pay practice and does not bill insurance directly, though many patients use HSA or FSA funds, and superbills are available on request. In-person appointments in Southlake are available by appointment only.
Sorrell MD PLLC1560 E Southlake Blvd, Ste 100
Southlake, TX 76092
817-518-3467 · info@sorrell-md.com
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