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Sorrell MD is a precision telemedicine practice founded by Luke Sorrell, MD FACP. Dr. Sorrell provides board-certified, one-on-one medical care to patients nationwide, specializing in hormone replacement therapy, body composition optimization, gut health, cardiovascular risk assessment, fertility optimization, and root cause medicine.

Sorrell MD operates entirely via telemedicine. You begin by booking a free discovery call to discuss your health goals. Dr. Sorrell then orders a comprehensive diagnostic workup, reviews the results with you, and builds a fully personalized protocol — all from the comfort of your home, with no commute or waiting room.

Luke Sorrell, MD FACP is a board-certified internal medicine physician and the founder of Sorrell MD. He practices via telemedicine, working directly with patients — never through physician assistants or rushed appointments — to optimize hormones, metabolism, gut health, cardiovascular risk, and fertility.

Sorrell MD serves patients nationwide via telemedicine, making expert precision medicine accessible regardless of your location.

Sorrell MD offers three membership programs plus two targeted, condition-specific programs. The memberships are the Longevity Program at $7,500/year, paid upfront (monthly appointments, unlimited messaging, and over $3,000 of included testing — Function Health labs twice yearly, annual gut microbiome, mitochondrial, and biological age testing, plus multi-cancer early detection screening); Longevity Program À La Carte at $350/month (the same physician access with testing and therapies chosen à la carte and billed separately); and the Hormone, Body Composition, Metabolic Optimization & Peptide Therapy program at $250/month (expert HRT, TRT, GLP-1 weight loss with muscle preservation, and MD-guided peptide therapy; labs and medications billed separately). Two focused programs target specific goals: the Gut Optimization program ($4,000 for 12 months with two Jona microbiome tests, or $2,500 for 6 months with one) and the Cardiovascular Risk program ($2,000 for a one-time comprehensive evaluation, or $4,000 for the 12-month program with ongoing management). Book a free discovery call to discuss pricing for your needs.

Sorrell MD is a direct-pay telemedicine practice and does not bill insurance directly. However, many patients use HSA or FSA funds to cover their care. Superbills can be provided for patients who wish to seek reimbursement from their insurance carrier.

You can book a free 30-minute discovery call directly through Sorrell MD's online scheduling page. There are no referrals required — just select a time that works for you at cal.com/luke-sorrell-md-facp/30min.

Yes. Sorrell MD offers Chat-Based Care powered by the Future Clinic platform, where you can message Dr. Sorrell directly for longevity and precision medicine questions. Your first message is free, a one-time focused consultation is $50, and unlimited monthly messaging is $50/month. It's ideal for quick clinical questions, follow-ups, or ongoing guidance without scheduling a video visit.

Sorrell MD offers hormone replacement therapy (HRT) for men and women, body composition optimization, gut health and microbiome optimization, cardiovascular risk assessment using advanced lipid and inflammatory markers, fertility optimization, and root cause analysis to identify the underlying drivers of chronic health issues.

Unlike conventional primary care, Sorrell MD focuses on deep diagnostics, root cause medicine, and personalized protocols rather than symptom management. Every patient works directly with Dr. Sorrell for extended, one-on-one consultations, with labs and treatment plans tailored to their unique biology, goals, and lifestyle.

Your first step is a free 30-minute discovery call where Dr. Sorrell reviews your health history, current symptoms, goals, and what you've already tried. If you're a good fit, he'll order a comprehensive diagnostic workup — advanced labs and functional testing well beyond what standard primary care provides. Once results are in, you'll have a detailed review visit to walk through findings and receive your personalized protocol.

Hormone replacement therapy (HRT) restores hormones to optimal levels when the body no longer produces enough on its own. At Sorrell MD, HRT includes testosterone optimization (TRT, clomiphene, enclomiphene) for men, bioidentical estradiol and progesterone for women, and thyroid optimization — all guided by comprehensive lab testing and ongoing monitoring.

A longevity medicine program is a proactive, comprehensive approach to health that goes beyond treating disease to optimizing how your body functions at every level. Sorrell MD's Longevity Program includes monthly physician appointments, unlimited messaging, Function Health labs twice yearly, annual gut microbiome, mitochondrial, and biological age testing, multi-cancer early detection screening, and personalized supplement, peptide, hormone, and prescription optimization — designed to maximize healthspan and performance.

Sorrell MD orders 100–200+ biomarkers depending on the program and clinical picture. Panels include a full hormonal profile (testosterone, estrogen, progesterone, thyroid, cortisol, DHEA-S, IGF-1), advanced metabolic markers (fasting insulin, HOMA-IR, HbA1c), cardiovascular markers (ApoB, Lp(a), hs-CRP, homocysteine, oxidized LDL), nutritional status (vitamin D, B12, folate, zinc, magnesium, omega-3 index), and functional markers selected based on symptoms. This is far beyond what a standard annual physical provides.

Precision telemedicine combines the accessibility of virtual healthcare with the depth of advanced diagnostics and personalized medicine. At Sorrell MD, it means receiving the same caliber of comprehensive testing, root-cause analysis, and individualized treatment protocols you'd expect at a top-tier academic center — all delivered via telemedicine with direct physician access, no geographic limitations, and no waiting rooms.

The Longevity Program ($7,500/year, paid upfront) is comprehensive concierge care — it includes over $3,000 of testing every year: Function Health labs twice yearly, annual gut microbiome, mitochondrial, and biological age testing, plus multi-cancer early detection screening. Longevity Program À La Carte ($350/month) offers the same physician access, with testing and therapies chosen à la carte and billed separately. The Hormone, Body Composition, Metabolic Optimization & Peptide Therapy program ($250/month) is focused optimization — expert HRT, TRT, body composition, weight loss including GLP-1 therapy with attention to preserving muscle mass, and MD-guided peptide therapy, with labs and medications billed separately. All include monthly appointments, unlimited messaging, and direct physician access.

Yes. Sorrell MD operates via telemedicine and serves patients nationwide across the United States. You can receive the same level of comprehensive diagnostics, personalized protocols, and direct physician access regardless of your location — all from the comfort of your home.

If you're searching for a longevity medicine doctor, Sorrell MD delivers expert care via telemedicine to patients nationwide — so geography isn't a barrier. Dr. Luke Sorrell, MD FACP is board-certified in internal medicine and specializes in longevity, hormone optimization, and precision diagnostics. Book a free discovery call to see if Sorrell MD is the right fit for your health goals.

Peptide therapy uses short chains of amino acids to target specific biological processes — supporting muscle recovery, fat metabolism, immune function, gut healing, sleep quality, and cellular repair. At Sorrell MD, Dr. Sorrell prescribes pharmaceutical-grade peptides through licensed 503A compounding pharmacies, with protocols tailored to each patient's labs, goals, and clinical picture. Peptide therapy is included in the Longevity Program, Longevity À La Carte, and Hormone, Body Composition, Metabolic Optimization & Peptide Therapy programs.

Key longevity biomarkers include hormones (testosterone, estradiol, thyroid panel, DHEA-S, IGF-1, cortisol), metabolic health markers (fasting insulin, HOMA-IR, HbA1c, fasting glucose), cardiovascular risk markers (ApoB, Lp(a), hs-CRP, homocysteine, oxidized LDL), nutrient status (vitamin D, B12, folate, magnesium, omega-3 index), and functional markers like biological age and mitochondrial function. Sorrell MD tests 100–200+ biomarkers per workup — far beyond what a standard annual physical covers — to build a complete picture of where your health stands and where it's heading.

GLP-1 receptor agonists (such as semaglutide and tirzepatide) work by mimicking a natural gut hormone that regulates appetite, blood sugar, and satiety. At Sorrell MD, Dr. Sorrell prescribes GLP-1 therapy as part of a comprehensive body composition program — not as a standalone weight-loss prescription. The protocol includes close monitoring of lean muscle mass, metabolic labs, and nutritional status to ensure patients lose fat while preserving muscle. GLP-1 therapy is available through the Hormone, Body Composition, Metabolic Optimization & Peptide Therapy program ($250/month).

Biological age testing measures how old your body is at a cellular level, as opposed to your chronological age. It uses biomarkers like DNA methylation patterns to estimate the pace of aging in your tissues and organs. At Sorrell MD, annual biological age testing is included in the Longevity Program ($7,500/year) and available à la carte to other patients. Tracking biological age over time shows whether your lifestyle, supplements, and treatment protocols are actually slowing aging — giving you an objective measure of what's working.